There is no BEMC talk in the month of October, but there is still a lot going on in the epi community!
JClub on Oct 16th: Please click on this link to see the chosen journal article. Note: for the first time ever, we will be reading a pre-print and submitting feedback as a group to the authors! Should be a cool experience to influence ongoing research, so don’t miss out!
IPH lecture on Oct 23rd: Professor John Gill is going to give a talk on “Understanding and communicating risk of rare but serious health complications – an example from living kidney donation” – click on this link to find out more and register for the event.
Our next regularly scheduled BEMC talk will be in November.
See you soon!
“An introduction to precisely and ggdag: Tools for modern methods in R” – a summary by Ana Sofia Oliveira Gonçalves
On the 4th September 2019, Malcolm Barrett held a lecture on the topic of “An introduction to precisely and ggdag: Tools for modern methods in R”. Malcolm Barrett is a PhD student in Epidemiology at the University of Southern California. He has experience in epidemiology and has worked with R studio.
During his lecture, he introduced two R packages that he has developed: “precisely” and “ggdag”. He then wrapped up his talk by sharing best practices in creating software for epidemiology analysis.
Malcolm first introduced the package “precisely”. Precisely is an R package which calculates sample size based on precision rather than power. It allows researchers to calculate sample sizes for common epidemiology measures, like risk differences, risk ratios and odds ratios. It can be used with R or just as a calculator on the web. It goes hand-in-hand with the recent discussion regarding statistical significance. During the discussion, he commented that the move away from p-values will still take some time. The motivation behind developing this package came from reading an article from Rothman and Greenland on planning study size based on precision. In this package, researchers need to set a desired precision, proportions of exposed to unexposed, group ratio and coverage. It also allows the calculation of precision given the sample size. The package shiny helps to run webapps, thus, people who do not work with R can still use precisely. He highlighted the common wrong interpretations of confidence intervals.
Malcolm proceeded to introduce his package “ggdag”. Ggdag is a package used to create causal diagrams in R. Dagitty does not always create beautiful plots and ggplot2 is the best data visualization tool at the moment. Hence, ggdag aims to integrate dagitty and ggplot2 (and ggraph which is actually part of ggplot2). Dagitty has powerful, robust algorithms and ggplot2 has unlimited flexibility. Ggdag also provides information (graphically) regarding the variables that need to be adjusted/controlled for.
Later on, he gave some insights on designing software for epidemiology. He mentioned that the developed software should be 1) very flexible, in order to automate tedious parts of analysis and be very loud about the difficult part, 2) expressive (modular code is better than monolithic functions), 3) able to fit into the ecosystem. He finished his lecture describing the package he is currently creating, which will be a tool to help clone datasets.
Dear Berlin-area Epidemiological Methods Enthusiasts,
We hope you had a great summer break!
We look forward to seeing you again at our September BEMC Talk in a few short weeks…
BEMC Talk: Wednesday, Sept. 4th, 2019 @ 4pm ·
“An introduction to precisely and ggdag: Tools for modern methods in R” -Malcolm Barrett (US)
**IMPORTANT: Location change: Forum 3, Hörsaal 3, Campus Virchow Klinikum (CVK) in Berlin-Wedding, 13353** ·
Please register here
Description: “Modern epidemiology gives us insight into study planning and causal inference, but the success of these approaches require friendly and accessible software. Malcolm will discuss two R packages he has developed as tools for implementing modern methods in study design and causal inference: precisely and ggdag. precisely is a study planning tool to calculate sample size based on precision rather than power. Calculating sample size based on precision focuses on the width of the confidence interval instead of statistical significance. precisely is a fast and flexible R implementation of the work by Rothman and Greenland on this subject, including a Shiny web app for calculating sample size. ggdag is a toolkit for working with causal directed acyclic graphs (DAGs), a central tool in causal inference. DAGs help identify many types of bias, like confounding, selection bias, and measurement error, as well as tell us how to correct for it. ggdag makes it easy to create, analyze, and plot DAGs in ggplot2.”
Other upcoming Berlin-area epi-related events:
Sept. 18th BEMC JClub article posted here ·
Early Oct no BEMC Talk!
Join us for the IPH lecture on Oct. 23rd · “Understanding and communicating risk of rare but serious health complications – an example from living kidney donation” – John Gill (Vancouver) ·
Oct. 16th, BEMC JClub article posted here ·
February 20-22nd, 2020: REWARD/EQUATOR Conference in Berlin (co-hosted by BIH-QUEST). Details & abstract submission here: https://www.reward-equator-conference-2020.com/