In light of the current situation with SARS-CoV-2 / COVID-19, ALL iN-PERSON BEMC EVENTS must be cancelled until further notice. We are working on bringing you digital content in the meantime! Stay tuned!
BEMC Talks are held on the first Wednesday of each month from 4-6pm at Hertwig–Hörsaal (Zweigbibliothek Campus Charité Mitte – Medizinische Bibliothek der Charité), Philippstr. 11, 10115 Berlin.
BEMC Talks consist of a 60-75 minute lecture followed by an interactive discussion session with the speaker and other participants. Please register in advance.
- January 8th
- Dan Chasman, Boston, USA
- “Understanding Population-based Migraine through Genome-wide Genetics”
- “In spite of recent advances in treatment, migraine remains among the top ranked conditions in burden of disability globally, especially among women. The prospect of additional migraine treatments is limited by sparse knowledge of fundamental underlying pathophysiologic mechanisms. Recently, genome-wide genetic approaches to migraine in the population are revealing biological functions relevant to migraine, providing insights into its clinical correlates, and addressing the underlying heterogeneity intrinsic to migraine’s clinical presentation.”
- February 5th
- Anders Huitfeldt,Oslo, Norway
- “A New Approach to the Generalizability of Randomized Trials”
- “Causal effects often differ between populations. When causal knowledge is obtained in one setting (for example in the study population of a large randomized controlled trial), extrapolation will usually be necessary in order to justify application of that knowledge in a different setting (for example in a clinically relevant target population). Several different frameworks have been proposed in order to formalize the extrapolation problem. These frameworks have different implications for how researchers should reason about what differences between populations must be accounted for. We propose a new type of causal model in order to formalize the problem, and show how this approach differs from other frameworks including the graphical models proposed by Bareinboim and Pearl. In contrast to these graphical models, our framework can be used to reproduce certain recommendations in the Cochrane Handbook.”
- March 4th
- Jan van den Brand, Nijmegen, the Netherlands
- “Joint Modeling for Dynamic Prediction Models: Examples from Nephrology”
- “The foundations of personalized medicine rest on the accurate prediction of disease course before and after treatment. Patients with chronic diseases have many biomarkers measured at frequent intervals at the out-patient department of a hospital. Moreover, measurements are increasingly taken longitudinally by patients themselves for example using mobile devices. However, such longitudinal data in healthcare remains untapped, as most current prediction models only use cross-sectional measurements and time-to-event data. On the other hand, state-of-the-art joint models that combine longitudinal and time-to-event data show great potential for personalized medicine. The R-package JMBayes by Rizopoulos and the lcmm package by Proust-Lima made the technology widely available and spurred further development of joint models for multiple longitudinal biomarkers, and multiple outcomes. However, developing a joint model is still not straightforward. In this talk I will offer an introduction to joint modeling and the rationale behind the technology. Next, I will go over some of the basic steps required to fit and evaluate a joint model, finally I will discuss common issues faced when building a joint model. In the discussion we could talk about some of the future prospects of joint modeling and prediction modeling in general.”
- no BEMC Talk, join our partner event: “Scientific Fraud – From Mendel to Staple”
- IPH Lecture Frits Rosendaal, Leiden, the Netherlands
- May 6th
- Sonia Boender, Berlin, Germany
- “Social Media for Public Health #SoMe4epis”
- June 3rd
- Stefan Konigorski, Potsdam, Germany
- “N-of-1 Trials”
- no BEMC Talk, join our partner event:
- IPH Lecture Kathy Rexrode, Boston, USA
- August – Summer Break!
- September 2nd
- Felicitas Kühne, Hall in Tirol, Austria
- “Avoiding Potential Biases in Real World Data Analysis by Emulating a Clinical Trial”
- October 7th
- Gemma Sharp, Bristol, UK
- “Mendelian Randomization, Negative Controls,and Sibling
Comparisons: Triangulating Causal Evidence to Study
Prenatal Influences on Offspring Health”
- November 4th
- Julia Ostermann, Berlin, Germany
- “Cost Analyses Using Claims Data in the Healthcare System”
- December 2nd
- Peter Tennant, Leeds, UK
- “Resolving Lord’s Paradox and Why Change-scores Don’t Capture Change”
Starting end of 2019: All BEMC Talks are held in the Hertwig–Hörsaal
Want to participate? Register for the event ahead of time- seating is limited!
Where do the talks take place? In Hertwig–Hörsaal Philippstr. 11, 10115 Berlin (Charite Mitte) . Follow our signs once you get to the building entrance.
What is the level? BEMC Talks are designed for an audience having at least some experience with epidemiological methods (intermediate to advanced level).
What is the language? English.
How about credits? Get all the details on our ‘For Students’ page (or click here).
For a list of past events, please visit our Archive.